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SEROQUEL 200 mg
® (quetiapine fumarate) may be a psychotropic agent belonging to a chemical category, the dibenzothiazepine derivatives. The chemical designation is 2[2(4dibenzo [(ii)b,f (/ii)] [1,4]thiazepin11yl1piperazinyl)ethoxy]ethanol fumarate (2:1) (salt). it's gift in tablets because the fumarate salt. All doses and pill strengths are expressed as milligrams of base, not as fumarate salt. Its molecular formula is C42H50N6O4S2•C4H4O4 and it's a molecular weight of 883.11 (fumarate salt). The structural formula is: Quetiapine fumarate may be a white to offwhite crystalline powder that is moderately soluble in water. SEROQUEL(/bb) is equipped for oral administration as twenty five mg (round, peach), fifty mg (round, white), a hundred mg (round, yellow), 200 mg (round, white), three hundred mg (capsuleshaped, white), and four hundred mg (capsuleshaped, yellow) tablets. Inactive ingredients are povidone, dibasic dicalcium phosphate dihydrate, microcrystalline cellulose, sodium starch glycolate, lactose monohydrate, magnesium stearate, hypromellose, polyethylene glycol and titanium dioxide. The twenty five mg tablets contain red ferric oxide and yellow ferric oxide and also the a hundred mg and four hundred mg tablets contain solely yellow ferric oxide. 12 CLINICAL PHARMACOLOGY12.1 Mechanism of Action The mechanism of action of SEROQUEL(/bb), like different medication having efficacy within the treatment of schizophrenia and bipolar disorder, is unknown. However, it's been proposed that the efficacy of SEROQUEL(/bb) in schizophrenia and its mood stabilizing properties in bipolar depression and mania are mediated through a mix of when does seroquel go generic dopamine sort two (D2) and serotonin sort two (5HT2) antagonism. Antagonism at receptors apart from dopamine and 5HT2 with similar receptor affinities might make a case for a number of the opposite effects of SEROQUEL(/bb). SEROQUEL’s antagonism of histamine H1 receptors might make a case for the somnolence observed with this drug. 1 INDICATIONS AND USAGE 1.1 Schizophrenia SEROQUEL(/bb) is indicated for the treatment of schizophrenia. The efficacy of SEROQUEL(/bb) in schizophrenia was seroquel sale established in *point2*

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